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Prof. Dr Dr h.c. Uwe Spetzger -  Specialist in Neurosurgery -Portrait

Prof. Dr Dr h.c. Uwe Spetzger

Director of the Clinic

Specialist in Neurosurgery

+49 721 9861 3226

Neurosurgery Karlsruhe - Prof. Dr Dr h.c. Uwe Spetzger

Treatment focus

  • Brain tumors
  • Brain hemorrhages and vascular malformations
  • Craniocerebral trauma
  • Spinal diseases
  • Neurosurgery in the area of peripheral nerves
  • Functional neurosurgery and movement disorders
  • Neurosurgical pain therapy


Municipal Hospital Karlsruhe
Neurosurgery Clinic
Moltkestraße 90, D-76133 Karlsruhe

P: +49 721 9861 3226 F: +49 721 974 3509

Consultation Hours:

Private outpatient clinic:
By telephone appointment

General outpatient clinic and special consultations:
Consultation hours by appointment - A referral is required!


Municipal Hospital Karlsruhe - Waiting roomProf. Dr Dr h.c. Uwe Spetzger - PortraitProf. Dr Dr h.c. Uwe Spetzger - OperationProf. Dr Dr h.c. Uwe Spetzger - OperationProf. Dr Dr h.c. Uwe Spetzger - OperationMunicipal Hospital Karlsruhe - Treatment roomMunicipal Hospital Karlsruhe - External view of the clinicMunicipal Hospital Karlsruhe - TeamMunicipal Hospital Karlsruhe - ImpressionsMunicipal Hospital Karlsruhe - External view of the clinicMunicipal Hospital Karlsruhe - Impressions

Medical Range

Range of Diagnostic Services


  • MRI
  • Electrophysiology (EEG, EMG, SEP, AEP)
  • Neuronavigation and monitoring
  • Stereotactic biopsy


Range of Therapeutic Services


  • Oncological Neurosurgery: brain tumors, brain metastases, meningiomas, pituitary adenomas, acoustic neuromas, gliomas
  • Vascular Neurosurgery: cerebral aneurysm, cerebral hemorrhage, vascular malformations, cavernoma, angioma, arteriovenous malformation (AVM)
  • Spinal Neurosurgery: herniated discs and stenoses (cervical and lumbar spine), spinal tumors and metastases, spinal injuries, vertebral fracture
  • Peripheral Nerve Surgery: nerve tumors, compression syndrome, nerve injuries
  • Pain Surgery: microvascular decompression according to Jannetta, intrathecal and neuromodulatory pain therapy, minimally invasive pain therapy procedures
  • Pediatric neurosurgery

More Information


Prof. Dr Dr h.c. Uwe Spetzger, is a specialist in neurosurgery and head of the Neurosurgical Clinic at the Karlsruhe Municipal Hospital.

As a maximum care clinic, the Neurosurgical Clinic under Prof. Spetzger has a unique position in treating space-occupying brain lesions, spinal cord, and craniocerebral trauma. In addition, the range of services includes all surgical therapy approaches for neurosurgical treatable diseases and injuries of the central and peripheral nervous system.

Brain Tumor Surgery in Karlsruhe

One of Prof. Spetzger’s central treatment focuses is surgical interventions for brain tumors. Both benign and malignant space-occupying brain tumors are removed with excellent care and maximum healthy brain tissue protection. In doing so, Prof. Spetzger and his team routinely use state-of-the-art microsurgical surgery procedures as well as neuronavigation, stereotaxy, ultrasound techniques, and intraoperative electrophysiological monitoring.

In addition to surgical therapy, postoperative treatment concepts in cooperation with the patient and family members play a central role. Therefore, the focus is on interdisciplinary collaboration with the specialist disciplines involved, such as oncology, radiology, and radiotherapy.

Therapy of Cerebrovascular Diseases

Malformations and bulges of the cerebral vessels can lead to cerebral hemorrhages if left untreated. If these are discovered, Prof. Spetzger and his team recommend surgery or endovascular therapy by neuroradiology. Depending on their location and size, brain aneurysms can be closed by coiling or clipping.

In coiling, a catheter placed through the groin is used to close the vascular outpouching using metal coils without surgery. Cerebral aneurysm clipping is a surgical procedure in which the defective vessel is closed from the outside with a metal clasp at the aneurysm site. In principle, surgical or endovascular treatment options are also available for vascular malformations. Prof. Spetzger decides which procedure is most suitable in close cooperation with the neuroradiology department, always adapted to the individual case.

Spine Surgery

Another primary focus of the neurosurgical clinic in Karlsruhe is spinal surgery. Prof. Spetzger and his team are experienced in the surgical treatment of herniated discs, spinal tumors, and spinal injuries. Prof. Spetzger attaches particular importance to the consideration of each individual case. For example, not every herniated disc requires surgery. But if nerves are destroyed by compression, the spine specialist in Karlsruhe has various surgical procedures available for the cervical and lumbar spine.

Prof. Spetzger and his neurosurgery specialists also use a range of surgical techniques and accompanying measures for spinal tumors, which the expert in spinal neurosurgery adapts individually to each case. His expertise includes tumors in the spinal cord or nerves and space-occupying lesions of the bony spine. In spinal cord tumor surgeries, the physician's focus is always on preserving the functions. Therefore, such surgeries are performed with function-preserving microsurgery.

Neurosurgical Pain Therapy – Help for Uncontrollable Pain Conditions

Neurosurgical pain therapy has various procedures available to eliminate pain that is otherwise difficult or impossible to control.

Microvascular Decompression

In trigeminal neuralgia and other nerve pain, a pinched nerve caused by vessels may be the cause. Decompression can correct the cause of severe nerve pain without further damaging the function of the nerve.

Intrathecal or Neurmodulatory Pain Therapy

When the cause of the pain cannot be directly controlled, severe pain can be suppressed with a pain pump or electrical stimulation. For example, for intrathecal pain therapy, a small tube is inserted into the spinal canal. This is connected to a pain pump, which can now continuously deliver pain medication directly to the point of action in the brain. This allows the dose to be reduced multiple times. Neuromodulatory pain therapy also attacks pain in the spinal cord area by implanting stimulating electrodes to help control it through electrical stimulation.

For more information, please visit the website of the Neurosurgical Clinic of the Karlsruhe Municipal Hospital.


Curriculum Vitae

2019 – 2020Medical Director Municipal Karlsruhe Clinic gGmbH
2002 – to dateDirector of the Neurosurgical Clinic, Municipal Karlsruhe Clinic
2000Habilitation at the Department of Neurosurgery, RWTH Aachen University. Venia legendi: Measurement of cerebral microcirculation during surgical therapy of cerebral aneurysms. Experimental and clinical evaluation using a Laser Doppler Scanning Imager
1999 – 2002Senior Physician, Department of Neurosurgery, Freiburg University Hospital
1999European Examination EANS/UEMS in Brussels, Belgium European Board Examination in Neurological Surgery and Appointed Fellow of European Board of Neurological Surgery
1999Research Scholarship of the Wilhelm-Tönnis Foundation e.V. of the German Society of Neurosurgery (DGNC) - Scientific Internship Department of Neurosurgery University of Illinois at Chicago, USA
1996 – 1999Senior Physician, Department of Neurosurgery, RWTH Aachen University Hospital
1994Dissertation at the Department of Gynecology, University of Heidelberg Mammary Biopsy of Benign Findings: Influence of Surgical Technique.
1990 – 1996Specialist Medical Training, Department of Neurosurgery, RWTH Aachen University Hospital
19902. State Medical Examination USA - Foreign Medical Graduate Examination in Medical Science (ECFMG clinical part)
1989Practical Year and State Medical Examination
19871. State Medical Examination USA - Foreign Medical Graduate Examination in Medical Science (ECFMG basic part)
1983 – 1988Studies of Human Medicine, Ruprecht-Karls-University Heidelberg and UZH Zurich

Honors & Awards

2016Executive Member of the Academia Eurasiana Neurochirurgica (AEN)
2012Honorary Member Royal College of Neurological Surgeons of Thailand
2011Guest Professorship First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China
2008Honorary Director and Scientific Cooperation Partner of the des First People’s Hospital in Changzhou, China
2008Honorary doctorate (Dr h. c.) and Faculty Member of Tbilisi State Medical University (TSMU) Tbilisi, Georgia
2007Award Germany - Land of Ideas. Category Science & Technology: Computer-Assisted Brain Surgery. Development of a Stereotaxy System for Intraoperative MRI.

Memberships in Scientific Societies

2019German Society for Neurotraumatology and Clinical Neurorehabilitation (DGNKN)
2016Founding Member of the International Society of Digital Medicine (ISDM)
2015Society for Minimally Invasive Spine Surgery (SMISS)
2010German Academy for Neurosurgery (DANC / GANS)
2009New European Surgical Academy (NESA)
2007German Spine Society (DGW)
2006Society for Medical Innovation and Technology (iSMIT)
2004Unit IV (Science and Teaching) Neurosurgical Academy for Education, Training and Continuing Education of the DGNC
2001Founding Member of the German Society for Computer- and Robot-Assisted Surgery (CURAC)
2001Cerebrovascular Section of the American Association of Neurological Surgeons (AANS / CNS)
1999German Society for Skull Base Surgery (DGSB)
1998Congress of Neurological Surgeons (CNS)
1997European Spine Society (EuroSpine)
1996German Society for Neurosurgery (DGNC)

Chair Societies & Conferences

2021Member of the Board of Directors KIT Freundeskreis und Fördergesellschaft e.V. (KFG)
2019President of the German Academy of Neurosurgery (DANC / GANS)
2016Vice-President of the International Society of Digital Medicine (ISDM)
2016Congress President of the German Academy of Neurosurgery (DANC / GANS)
2015Congress President of the 66th Annual Meeting of the German Society for Neurosurgery (DGNC)
2013President of the International Society of Medical Innovation and Technology (iSMIT)
2008Steering Committee Member, International Society for Medical Innovation and Technology (iSMIT)
2007Congress President of the 6th Annual Meeting of the Society for Computer- and Robot-Assisted Surgery (CURAC 2007)


  • Dr George Kiriyanthan
    Directing Senior Physician
  • Dr Alexander König
    Senior Physician
  • Dr Gerd Winkler
    Senior Physician
  • Dr Andrej von Schilling
    Senior Physician
  • Dr Till Brombach
    Functional Senior Physician
  • Dr Peter Patlevic
    Specialist Physician

Research & Training



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Transport Connections

Main Train Station Karlsruhe4.8 km
Karlsruhe / Baden-Baden Airport41 km
Stuttgart Airport78 km
Strasbourg Airport, France99 km
Frankfurt Airport130 km

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Prof. Dr Dr h.c. Uwe Spetzger

Director of the Clinic

Municipal Hospital Karlsruhe

Neurosurgery Clinic

Moltkestraße 90, D-76133 Karlsruhe

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