Gastroenterology & Hepatology Clinic in Karlsruhe: Prof. Dr Thomas Zöpf

Prof. Dr Thomas Zöpf
Clinic Director
Specialist in Gastroenterology
Karlsruhe, Germany

ViDia Clinics, situated at the St Vincentius Clinics - Logo

Treatment Focus

  • Gastric diseases
  • Tumours of the digestive tract
  • Biliary and liver diseases
  • Bowel diseases
  • Pancreatic diseases
  • Dysfunctions (functional dyspepsia and irritable bowel syndrome)

Medical Range

Range of Diagnostic Services

  • Gastroscopy
  • Colonoscopy
  • Diagnostic and therapeutic endosonography
  • Single-balloon endoscopy (small bowel endoscopy)
  • ERCP with 3D technology (bile duct endoscopy)
  • Capsule endoscopy
  • Cholangioscopy (endoscopy of the biliary tract)
  • Endosonography (ultrasound examination from inside)
  • Endosonographic puncture
  • PTCD (radiological representation of the bile ducts from the outside)
  • Pancreatoscopy
  • Mini-laparoscopy (mini-abdominal-endoscopy)
  • Chromoendoscopy (virtual and real staining methods of the mucous membrane)
  • Magnification endoscopy

Range of Therapeutic Services


  • Ulcer diseases (gastric ulcers and duodenal ulcers)
  • Functional dyspepsia and irritable bowel syndrome
  • Inflammatory bowel disease: Crohn's disease and ulcerative colitis
  • Colonic polyps
  • Diseases of the small bowel
  • Pancreatic diseases


  • Liver diseases (liver cirrhosis, hepatitis, liver cysts)
  • Bile duct diseases
  • Sclerosing cholangitis
  • Bile duct stones
  • Autoimmune diseases of the liver and bile ducts

Gastroenterological Oncology

  • Colon cancer
  • Stomach cancer
  • Liver cancer
  • Pancreatic cancer
  • Gall bladder cancer
  • Bile duct cancer (cholangiocellular carcinoma)

Endoscopic Therapeutic Procedures

  • Polypectomy (endoscopic removal of benign tumours)
  • Endoscopic full-thickness resection (eFTR)
  • Endoscopic mucosal resection (endoscopic resection)
  • Endoscopic submucosal dissection (large-scale resection)
  • Endoscopic foreign body extraction
  • Dilatation of stenoses (expanding constrictions)
  • Photodynamic therapy (destruction of tumours using laser light)
  • Insertion of plastic stents
  • Insertion of self-expanding metal stents
  • Drainage of pancreatic pseudocysts
  • Pancreatic necrosis
  • Zenker's diverticulum
  • Achalasia
  • Haemostasis procedures
  • Endoscopic attachment of feeding tubes (PEG, PEJ)
  • Endoscopic fragmentation of bile duct and pancreas stones using an EHL probe
  • Haemorrhoid ligation (ligation of haemorrhoids using rubber bands)

About Prof. Dr Thomas Zöpf – Chief Physician of Gastroenterology in Karlsruhe

Prof. Dr Thomas Zöpf is specialist and clinic director of the gastroenterology department at St Vincentius Clinics and the Deaconess Hospital in Karlsruhe in Baden-Württemberg, Germany. The competent and patient-oriented team around Prof. Zöpf treats all illnesses of the gastrointestinal tract including organs connected to it such as liver, gallbladder, and pancreas according to latest scientific findings. The main focus is based on endoscopy and gastroenterological oncology.

Gastroenterology and Hepatology in Karlsruhe: a Specialized Clinic in Karlsruche at Two Different Locations

The clinic of Gastroenterology and Hepatology is represented in Karlsruhe at two distinct locations: in the Deaconess Hospital and at the St Vincentius Clinics (ViDia). The ViDia clinics have laid down in their guidelines both the careful and charitable treatment of their patients, as well as their holistic approach and effective nursing approach. Close cooperation with the departments of surgery, radiology and oncology ensures the best possible and gentle treatment at every stage of a disease. For special questions, a team of specialists from other disciplines such as cardiology, diabetology, nutritional medicine, intensive care or palliative care are available for consultations. Since February 2013, the Deaconess Hospital is in possession of one of the most modern endoscopy departments in Europe (ZEuS).

Treatment Focus of Prof. Zöpf

In cases of diseases of the gastrointestinal tract, liver, gall bladder or pancreas, the quality of a patient’s life is often severely limited. A humane approach to patients is therefore a particular concern of Prof. Zöpf and his gastroenterology team in Karlsruhe. One of their special expertise encompasses the endoscopic diagnosis and treatment of afflictions of the digestive tract.

Gastrointestinal Diseases

Common diseases of the digestive tract include functional disorders of the stomach. The term "irritable stomach" hides a whole series of varied complaints in the upper abdomen. Those causes cannot always be clarified clearly and are in many cases accompanied by intestinal complaints such as the irritable bowel syndrome. The disease pattern of an irritable bowel show constipation as well as diarrhoea, bloating or abdominal pain, although there is no pathological change present in the intestine. For diagnosis and treatment, Prof. Zöpf has state-of-the-art and highly specialised devices at his disposal at the Gastroenterology clinic in Karlsruhe.

A gastric ulcer is a deep wound of the gastric mucosa which nowadays rarely requires surgery but is treated with medication instead. Duodenal ulcers occur even more often. These are usually also treated medically to prevent destruction of the stomach or intestinal wall.

Likewise patients with inflammatory bowel disease such as Crohn's disease or ulcerative colitis, are professionally advised and looked after at the gastrointestinal clinic in Karlsruhe. If small intestine diseases are suspected, this area of the intestine can be examined by means of capsule endoscopy (swallowing a camera capsule) or balloon endoscopy ("threading" of the small intestine by using an inflatable balloon). If necessary, both method are used simultaneously.

Diagnosis and Treatment of Liver Diseases (Hepatology)

Another focal point of the Gastroenterology clinic in Karlsruhe are diseases of the liver along with their consequences, such as liver cirrhosis, benign and malignant liver tumours, or inflammatory changes in the liver (hepatitis). For precise diagnosis, special contrast-media ultrasound procedures and gentle mini-laparoscopies are available. These endoscopic examination methods are characterised by minimal exposure to access points of just a few millimetres in addition low-stress and retention of only smallest, barely visible scars for the patient.

With liver cirrhosis, healthy tissue is broken down and replaced by non-functional connective tissue. Since this disease cannot be remedied but only delayed in its course, close monitoring and customised medications are necessary. Inpatient treatment is also required for certain forms of hepatitis. The team headed by Prof. Zöpf cares for patients with liver diseases both conservatively and surgically, depending on the extent of the disease.

Diseases of the Gall Bladder and pancreas

For diseases and inflammation of the gallbladder, bile ducts, and gallstones, all current modern methods, such as cholangioscopy, electrohydraulic lithotripsy (EHL) for the destruction of trapped bile duct stones, and photodynamic therapy (PDT) of bile duct tumours are available at the Gastrointestinal Clinic in Karlsruhe

Inflammation of the pancreas (pancreatitis) causes severe pain in the upper abdomen, nausea, and vomiting. Pancreatic tumours are often recognised late because they do not cause symptoms at an early stage. Numerous endoscopic treatment options are available for chronic pancreatitis.

Gastroenterological Oncology

Tumours of the gastrointestinal tract and the liver are among the most common malignant diseases. The Gastroenterology Clinic in collaboration with the Surgical Clinic specialises in the diagnosis and treatment of tumours of the gastrointestinal tract, liver, and pancreas. All patients are discussed in a joint weekly, interdisciplinary conference (Tumour Board) in order to ensure the best possible treatment according to latest findings.

Centre for Endoscopy and Sonography, Karlsruhe (ZEuS)

A special focus of the Gastroenterology and Hepatology Center of the ViDia Clinics in Karlsruhe is diagnostic and therapeutic endoscopy of the digestive organs. The cross-location Centre for Endoscopy and Sonography (ZEuS) is one of the most modern departments in the region and is one of the largest endoscopy departments in Southwest Germany. Every year, about 8,000 endoscopic examinations and procedures are performed at the two Karlsruhe clinic sites - the Deaconess Hospital and the St Vincentius Clinics. By focusing on an area with a large case numbers, a high level of expertise and experience is guaranteed.


Gastroscopy allows Prof. Zöpf and his team to examine the mucous membranes of the stomach, oesophagus and duodenum. Stomach ulcers, inflammation of the oesophagus including malignant changes can hereby be detected. In gastroscopy, a tube with a video camera is inserted through the mouth and oesophagus into the stomach.


Colonoscopy is an important tool in colorectal cancer screening and diagnostics. During the examination, the intestinal mucous membrane is thoroughly inspected by the experienced gastroenterologists in Karlsruhe using a video camera. Conspicuous changes such as polyps can be directly removed endoscopically and sent to pathology for a more detailed diagnosis.

ERCP (Endoscopically Retrograde Cholangio Pancreatography)

For the diagnosis of diseases of the bile duct and pancreas, a special x-ray system is available in the Gastroenterology Clinic in Karlsruhe which not only provides excellent image quality but also a three-dimensional view of the bile ducts. Diseases requiring treatment such as stenosis of the bile duct can be repaired immediately by dilation or by inserting a stent.

Greatest Possible Patient Comfort and Safety

The Centre for Endoscopy and Sonography in Karlsruhe (ZEuS) has a high-quality endoscopy department with three examination rooms available at each location. The technical equipment includes the latest generation of video endoscopes. All endoscopy specialist nurses are specially trained to provide outpatient and inpatient care in a comfortable and safe atmosphere. Most endoscopic examinations are performed by administering an intravenous sleep-inducing drug. With this approach, the endoscopies are perceived as less stressful by patients. Gentle music plays in the examination rooms to help provide a relaxed examination atmosphere.

You can find further information on the website of Prof. Dr Thomas Zöpf.

Curriculum Vitae

January 2017 – present Director of the Gastroenterology/Hepatology Clinic of the ViDia Clinics in Karlsruhe
May 2012 – December 2016 Chief Physician of the Clinic of Internal Medicine, Deaconess Hospital, Karlsruhe-Rüppurr
July 2008 – April 2012 Chief Physician of the Medical Clinic, Sana Clinics, Düsseldorf, located in Gerresheim
April 2003 – June 2008 Head Senior Physician of Central Endoscopy in the Gastroenterology and Hepatology Clinic (Director: Prof. Dr G. Gerken), University Hospital, Essen
January 1997 – March 2003 Medical Clinic C (Director: Prof. Dr JF Riemann), Ludwigshafen City Clinic
July 1992 – December 1996 Internal Medicine I (Director: Prof. Dr G. Adler), University of Ulm Hospital
1985 – 1992 Study of human medicine, University of Ulm
1984 – 1985 Study of physics, University of Ulm

Medical Team

  • Dr Gert Zachmann
    Head Senior Physician
    Head of Endoscopy at the Deaconess Hospital
  • Dr Andreas Deimel
    Executive Head Senior Physician
    Head of Endoscopy at the St Vincentius Clinics
  • Dr Victor J. Keim
    Senior Physician
    Head of the Ultrasound Laboratory
  • Adolf Kroeber
    Senior Physician
    Head of the Functional Laboratory
  • Martin Mörtel
    Senior Physician
    Head of the Interdisciplinary Emergency Department
  • Nevena Baeva, MScNS
    Senior Physician


Karlsruhe Central Railway Station 1.5 km
Stuttgart Airport 82 km
Frankfurt Airport 139 km

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Prof. Dr Thomas Zöpf
Clinic Director

ViDia Clinics, situated at the St Vincentius Clinics
Gastroenterology, Hepatology
Südendstraße 32, D-76135 Karlsruhe

T: +49 721 9861 3019
F: +49 721 8108 3609


By arrangement

Deaconess Hospital Location
Gastroenterology, Hepatology
Diakonissenstraße 28, D-76199 Karlsruhe

T: +49 721 9861 3020
F: +49 721 889 3908

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